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Drug intelligence / Profile preview
[68Ga]Ga-PSMA
- Development stage
- Unknown
- Lead developer
- Union Hospital
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
[68Ga]Ga-PSMA is a gallium-68 radiolabeled radiopharmaceutical targeting prostate-specific membrane antigen (PSMA), also known as glutamate carboxypeptidase II. It is widely used as a positron emission tomography (PET) imaging agent to detect, stage, and monitor PSMA-expressing tumors. While primarily utilized in prostate cancer, PSMA is also overexpressed on the neovasculature of various other solid tumors, including clear cell renal cell carcinoma (ccRCC), making [68Ga]Ga-PSMA a valuable diagnostic tool for evaluating tumor burden, staging, and treatment response in non-prostate malignancies as well.
- Other names
- 68Ga-PSMA[68Ga]Ga-PSMAGa-68 PSMAGa68 PSMAGa 68 PSMAGallium-68 PSMAGallium68 PSMAGallium 68 PSMA
02
Targets
PSMA (Prostate-specific membrane antigen)
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